Development status of domestic pharmaceutical intermediates

Pharmaceutical intermediates refer to intermediate chemicals made in the process of chemical synthesis, which belong to fine chemical products. The upstream industry is the basic chemical raw material manufacturing industry, and the downstream industry is the chemical raw material and preparation manufacturing industry. In the early stage of the development of the pharmaceutical intermediates industry, due to small investment, higher profit level than ordinary chemical products, and the market access threshold is relatively low, resulting in a large number of small chemical enterprises to join the field of pharmaceutical intermediates.
At present, China's pharmaceutical intermediates industry has a high degree of marketization, and the overall performance is characterized by small and medium-sized enterprises, concentrated production areas, stable business scale, low process technology level, and serious product homogenization. In recent years, the development of new pharmaceutical intermediates has become more and more difficult, and the competition of traditional products has become more and more fierce, coupled with the impact of national environmental protection policies, the overall scale of the pharmaceutical intermediates industry has shown a downward trend.

According to the data of Intelligent Research consulting, pharmaceutical intermediates are a single chemical substance of high purity obtained through chemical or biological reaction, similar to the production method of chemical apis, so China's chemical API manufacturing enterprises usually also produce pharmaceutical intermediates, and its development level is closely related to the development of chemical apis and chemical pharmaceutical preparations. In the future, with the expiration of a large number of patented drugs, generic drugs will bring broad market space and good development opportunities to pharmaceutical intermediates.